115 N 6th St, St. Louis, MO, 63101  (Show me directions) Show Map

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  Monday to Friday: 07:30 to 17:00 , Saturday to Sunday: Closed

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Enjoy clean, sanitized vehicles and a low-touch rental process with Enterprise Rent-A-Car in St. Louis. No matter when or where you want to start your next adventure, when you're ready, we're ready to fill your car rental needs at one of our 7,000+ locations in nearly 100 countries and territories.

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